Donald Arlen "Donnie" Pritchett is the loud and obnoxious brother of Jay Pritchett and is currently suffering from prostate cancer. Donnie appears, at first, to have an abrasive, dysfunctional relationship with his brother, which mostly consists of frequent physical assaults and insults to one another, much to the confusion of Gloria. However, when Jay discovers that his brother is suffering from cancer he is much more sympathetic and the two share an emotional moment.
- Donnie is both uncredited and does not physically appear in the episode "Hawaii", however his voice is heard. It is unknown if that was the voice of Jonathan Banks who played the character in "The Musical Man".
- It is revealed that Donnie is younger than Jay in "Spring-a-Ding-Fling" when Jay calls him "my baby brother". Also in "The Musical Man", Donnie said that Jay cared about him since they were 8 and 10 years old, signifying that the two brothers are 2 years old apart.