Irene Pritchett is Donnie Pritchett's wife and also Michael Pritchett's mother, as well as the grandmother of Melanie Pritchett and the sister-in-law of Jay Pritchett.

In "Hawaii, Donnie mentioned over Jay's phone that Irene's begging him, but Jay cuts him off and goes after Gloria, so what she was begging of is unknown.

In "The Musical Man", Irene calls her husband cause he didn't tell her he landed safely, then later he tells her "How the hell should I know where your glasses are?", and when Jay and Donnie make up and Donnie tells Jay that he'll be fine, he says that Irene lost 20 pounds due to stress.


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